A novel therapeutic strategy for hepatocellular carcinoma: Immunomodulatory mechanisms of selenium and/or selenoproteins on a shift towards anti-cancer

BK Wu, QH Chen, D Pan, B Chang, LX Sang - International …, 2021 - Elsevier
… pathway in the soil, and animals and humans consume these sources as vegetables, meats…
and glycogen synthase kinase 3 beta in human liver cancer stem cells in vitro, which leads to …

[HTML][HTML] Selenium as a bioactive micronutrient in the human diet and its cancer chemopreventive activity

D Radomska, R Czarnomysy, D Radomski… - Nutrients, 2021 - mdpi.com
… , the liver, and/or muscles in rats and chickens. Since then, its impact on the human body …
Se in the fertility and reproduction of humans and animals. A deficiency of this trace element …

Antioxidant Enzyme Activities in Ascorbic Acid and Selenium Applied Hepatocellular Carcinoma Cells

BM Balkan, Ö Meral, G Kismali, T Sel - Journal of the Turkish …, 2020 - dergipark.org.tr
… on L-selenomethionine, SeO2 application, and CAT activities … (35) demonstrated that AA
could lead to liver cancer cells' … studies and experimental animal models supported that Se …

[HTML][HTML] Selenium anticancer properties and impact on cellular redox status

L Kuršvietienė, A Mongirdienė, J Bernatonienė… - Antioxidants, 2020 - mdpi.com
… chemotherapeutic application of redox active selenium compounds… Two metabolic pools of
Se are characteristic to human and animal … Se asserts chemopreventive activity when used at …

[图书][B] Selenium compounds as a novel class of experimental cancer chemotherapeutics

AK Selvam - 2021 - search.proquest.com
application in cancer chemotherapeutics. This simple drug … % in animals bearing xenografts
of the drug-sensitive tumor (… and chemopreventive properties by several preclinical studies. …

[HTML][HTML] Antitumor effects of selenium

SJ Kim, MC Choi, JM Park, AS Chung - International Journal of Molecular …, 2021 - mdpi.com
… see clinical application of this compound in cancer patients. … Furthermore, animal and
human intervention studies are … used for chemoprevention and blocking tumor metastasis. …

Selenium-based novel epigenetic regulators offer effective chemotherapeutic alternative with wider safety margins in experimental colorectal cancer

P Ghanghas, M Sharma, D Desai, K Raza… - … Trace Element Research, 2021 - Springer
… with SAHA limit its clinical application. Based on the redox-… risk of lung, liver, bladder,
esophagus, and stomach cancer [2]. … The animals and protocols used in the present study were …

[HTML][HTML] Selenium compounds as novel potential anticancer agents

D Radomska, R Czarnomysy, D Radomski… - International Journal of …, 2021 - mdpi.com
… Se compounds can have chemopreventive activity, studies … using inorganic selenium
compounds on animals. Meanwhile, … harmful properties and possible application in human trials in …

[HTML][HTML] Natural Sources of Selenium as Functional Food Products for Chemoprevention

M Dobrzyńska, S Drzymała-Czyż, D Woźniak… - Foods, 2023 - mdpi.com
… [141] observed no primary liver cancer after 4 years of … and animal studies confirmed the
beneficial chemoprevention … It is of note that the chemopreventive dose of Se (200 µg/day) is …

Chemopreventive mechanism of action by oxidative stress and toxicity induced surface decorated selenium nanoparticles

S Menon, VK Shanmugam - Journal of Trace Elements in Medicine and …, 2020 - Elsevier
… can be lethal to the aquatic organisms, humans, and animals[29]. … One such example is the
treatment of HBV-infected liver cancer … The application of selenium nanoparticles in clinical …